Here is a list of my publications, which can also be found on my Google Scholar and OrcID pages. If you are unable to access a publication for any reason and would like to request a copy, please contact me directly at lucas.wheeler@colorado.edu. * indicates corresponding authorship.

Research and review articles



2021


Wheeler LC, Harms MJ (2021). Were ancestral proteins less specific? Molecular Biology and Evolution (A version of this article is also available at bioRxiv; doi: 10.1101/2020.05.27.120261)

2020


Wheeler LC*, Wing BA, Smith SD (2020). Structure and contingency determine mutational hotspots for flower color evolution Evolution Letters; doi:10.1002/evl3.212 (a version of this article is also available on bioRxiv)

Wheeler LC, Perkins A, Wong CE, Harms MJ (2020). Learning Peptide Recognition Rules for a Low-Specificity Protein. Protein Science; doi.org/10.1002/pro.3958. (A version of this article is also available at bioRxiv; doi: 10.1101/2020.06.02.131086v1.)

2019


Wheeler LC*, Smith SD (2019). Computational modeling of anthocyanin pathway evolution: Biases, hotspots, and trade-offs. Integrative and Comparative Biology; doi:10.1093/icb/icz049. (A version of this article is also available at bioRxiv; doi: 10.1101/511089.)

2018


Duvvuri H, Wheeler LC, Harms MJ (2018). pytc: open source python software for global analyses of isothermal titration calorimetry data. Biochemistry; doi: 10.1021/acs.biochem.7b01264. (A version of this article is also available at bioRxiv)

Wheeler LC, Anderson JA, Morrison AJ, Wong CE, Harms MJ (2018). Conservation of specificity in two low-specificity proteins. Biochemistry; doi: 10.1021/acs.biochem.7b01086 (a version of this article is also available at bioRxiv)

2017


Wheeler LC, Harms MJ (2017). S100A5 binds Ca2+ and Cu2+ independently. BMC Biophysics; doi: 10.1186/s13628-017-0040-y

2016


Wheeler LC, Donor MT, Prell JS, Harms MJ (2016). Multiple Evolutionary Origins of Ubiquitous Cu 2+ and Zn 2+ Binding in the S100 protein Family. PLoS ONE 11(10): e0164740. doi:10.1371/journal.pone.0164740

Wheeler LC, An-Lim S, Marqusee S, Harms MJ (2016). The thermostability and specificity of ancient proteins. Current Opinions in Structural Biology. doi: 10.1016/j.sbi.2016.05.015 (LCW and SAL contributed equally to the work)

Doctoral dissertation



Wheeler LC (2017). Evolution of Metal and Peptide Binding in the S100 Protein Family. ProQuest, GitHub.